The Science Treatment of Bipolar Disorder Huberman Lab Podcast 82

In this episode I explain the biology symptoms causes and types of bipolar disorder sometimes called bipolar depression I discuss neuroplasticity and how the brain normally regulates mood energy and perceptions then I contrast that with the biology of bipolar disorder which is characterized by extremes of energy and mood e g mania and depression I outline the mechanisms through which bipolar disorder manifests in the brain including deficits of interoception and reduced connections between the parietal and limbic systems I also outline how treatment options such as lithium work in part through homeostatic plasticity I discuss not only lithium but also the treatment of bipolar with ketamine different talk therapies electroconvulsive therapy transcranial magnetic stimulation and nutraceuticals including Omega-3 and Inositol supplementation This episode should interest anyone who has or knows someone with bipolar disorder and more broadly those interested in how the brain works to create a balance between thoughts energy levels focus and mood HubermanLab Bipolar BipolarDisorder Thank you to our sponsors InsideTracker a https 3A 2F 2Finsidetracker com 2Fhuberman a ROKA a https 3A 2F 2Fwww roka com 2Fhuberman a Blinkist a https 3A 2F 2Fwww blinkist com 2Fhuberman a Supplements from Momentous a https 3A 2F 2Fwww livemomentous com 2Fhuberman a Social Website Instagram - a https 3A 2F 2Fwww instagram com 2Fhubermanlab a Twitter - a https 3A 2F 2Ftwitter com 2Fhubermanlab a Facebook - a https 3A 2F 2Fwww facebook com 2Fhubermanlab a TikTok - a https 3A 2F 2Fwww tiktok com 2F 40hubermanlab a Website - a https 3A 2F 2Fhubermanlab com a Newsletter - a https 3A 2F 2Fhubermanlab com a neural-network Subscribe to the Huberman Lab Podcast Apple Podcasts a https 3A 2F 2Fapple co 2F3thCToZ a Spotify a https 3A 2F 2Fspoti fi 2F3PYzuFs a Google Podcasts a https 3A 2F 2Fbit ly 2F3amI809 a Other platforms a https 3A 2F 2Fhubermanlab com a follow Full show notes links to peer-reviewed articles a https 3A 2F 2Fhubermanlab com a the-science-and-treatment-of-bipolar-disorder Timestamps 00 00 00 Bipolar Disorder 00 02 23 Momentous Supplements 00 03 42 Tool Appetite Suppression GLP-1 Parallel Pathways Yerba Mate 00 10 23 InsideTracker ROKA Blinkist 00 14 24 Prevalence Severity of Bipolar Disorder 00 16 30 Bipolar Disorder I Diagnostic Criteria of Mania 00 28 58 Bipolar Disorder II Individual Variability 00 33 07 Bipolar I vs Bipolar II Manic Depressive Symptom-Free States 00 38 20 Consequences of Bipolar Disorder Heritability 00 46 53 Bipolar Disorder vs Borderline Personality Disorder 00 51 51 Mania Depression Negative Impacts 00 53 06 History of Lithium Treatment 01 02 44 Lithium Treatment Side-Effects 01 05 05 Effects of Lithium BDNF Anti-inflammatory Neuroprotection 01 10 10 Neural Circuits of Bipolar Disorder Interoception Hyper- vs Hypoactivity 01 17 11 Neural States Mania Parietal Lobe Limbic System 01 22 58 Homeostatic Plasticity Synaptic Scaling Lithium Ketamine 01 36 00 Talk Therapies Cognitive Behavioral Therapy Family-Focused Therapy Interpersonal Social Rhythm Therapy 01 43 18 Electroconvulsive Therapy ECT Transcranial Magnetic Stimulation rTMS 01 48 01 Psylocibin Cannabis 01 51 50 Lifestyle Support Supplements Inositol Omega-3 Fatty Acids 02 03 31 Omega-3s Membrane Fluidity Neuroplasticity 02 06 44 Mania Creativity Occupations 02 15 33 Bipolar Disorder Diagnosis Neural Circuits Treatment 02 17 45 Zero-Cost Support YouTube Feedback Spotify Apple Reviews Sponsors Momentous Supplements Instagram Twitter Neural Network Newsletter The Huberman Lab Podcast is for general informational purposes only and does not constitute the practice of medicine nursing or other professional health care services including the giving of medical advice and no doctor patient relationship is formed The use of information on this podcast or materials linked from this podcast is at the user s own risk The content of this podcast is not intended to be a substitute for professional medical advice diagnosis or treatment Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions Title Card Photo Credit Mike Blabac - a https 3A 2F 2Fwww blabacphoto com a

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