Dr Oded Rechavi Genes the Inheritance of Memories Across Generations Huberman Lab Podcast

In this episode my guest is Oded Rechavi Ph D professor of neurobiology at Tel Aviv University and expert in how genes are inherited how experiences shape genes and remarkably how some memories of experiences can be passed via genes to offspring We discuss his research challenging long-held tenets of genetic inheritance and the relevance of those findings to understanding key biological and psychological processes including metabolism stress and trauma He describes the history of the scientific exploration of the heritability of acquired traits and how epigenetics and RNA biology can account for some of the passage of certain experience-based memories He discusses the importance of model organisms in scientific research and describes his work on how stressors and memories can be passed through small RNA molecules to multiple generations of offspring in ways that meaningfully affect their behavior Nature vs nurture is a commonly debated theme Dr Rechavi s work represents a fundamental shift in our understanding of that debate as well as genetic inheritance brain function and evolution Thank you to our sponsors AG1 Athletic Greens a https 3A 2F 2Fathleticgreens com 2Fhuberman a ROKA a https 3A 2F 2Froka com 2Fhuberman a HVMN a https 3A 2F 2Fhvmn com 2Fhuberman a Eight Sleep a https 3A 2F 2Feightsleep com 2Fhuberman a InsideTracker a https 3A 2F 2Fwww insidetracker com 2Fhuberman a Supplements from Momentous a https 3A 2F 2Fwww livemomentous com 2Fhuberman a Huberman Lab Social Website Instagram a https 3A 2F 2Fwww instagram com 2Fhubermanlab a Twitter a https 3A 2F 2Ftwitter com 2Fhubermanlab a Facebook a https 3A 2F 2Fwww facebook com 2Fhubermanlab a TikTok a https 3A 2F 2Fwww tiktok com 2F 40hubermanlab a LinkedIn a https 3A 2F 2Fwww linkedin com 2Fin 2Fandrew-huberman a Website a https 3A 2F 2Fhubermanlab com a Newsletter a https 3A 2F 2Fhubermanlab com a neural-network Dr Rechavi Academic Profile a https 3A 2F 2Fen-lifesci tau ac il 2Fprofile 2Fodedrech 66 a Lab Website a https 3A 2F 2Fwww odedrechavilab com a Twitter a https 3A 2F 2Ftwitter com 2FOdedRechavi a TEDx Talk a https 3A 2F 2Fwww ted com 2Ftalks 2Foded rechavi transgenerational biology 3Flanguage 3Den a Articles Neuronal Small RNAs Control Behavior Transgenerationally a https 3A 2F 2Fbit ly 2F2HZxrzO a Transgenerational Inheritance of an Acquired Small RNA-Based Antiviral Response in C elegans a https 3A 2F 2Fbit ly 2F41xRf47 a Timestamps 00 00 00 Dr Oded Rechavi 00 02 08 Sponsors ROKA HVMN Eight Sleep 00 06 04 DNA RNA Protein Somatic vs Germ Cells 00 14 36 Lamarckian Evolution Inheritance of Acquired Traits 00 22 54 Paul Kammerer Toad Morphology 00 28 52 AG1 Athletic Greens 00 30 06 James McConnell Memory Transfer 00 37 31 Weismann Barrier Epigenetics 00 45 13 Epigenetic Reprogramming Imprinted Genes 00 50 43 Nature vs Nurture Epigenetics Offspring 00 59 06 Generational Epigenetic Inheritance 01 09 03 Sponsor InsideTracker 01 10 20 Model Organisms C elegans 01 21 50 C elegans Inheritance of Acquired Traits Small RNAs 01 26 02 RNA Interference C elegans Virus Immunity 01 34 13 RNA Amplification Multi-Generational Effects 01 38 41 Response Duration Environment 01 47 50 Generational Memory Transmission RNA 01 59 36 Germ Cells Behavior Body Cues 02 04 48 Transmission of Sexual Choice 02 11 22 Fertility Human Disease 3-Parent In Vitro Fertilization IVF RNA Testing 02 17 56 Deliberate Cold Exposure Learning Memory 02 29 26 Zero-Cost Support Spotify Apple Reviews YouTube Feedback Sponsors Momentous Social Media Neural Network Newsletter Title Card Photo Credit Mike Blabac - a https 3A 2F 2Fwww blabacphoto com a The Huberman Lab podcast is for general informational purposes only and does not constitute the practice of medicine nursing or other professional health care services including the giving of medical advice and no doctor patient relationship is formed The use of information on this podcast or materials linked from this podcast is at the user s own risk The content of this podcast is not intended to be a substitute for professional medical advice diagnosis or treatment Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions

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